Stereotactic body radiation therapy for elderly patients with small hepatocellular carcinoma: a retrospective observational study.

ABSTRACT:

Background/aim

We aimed to investigate the efficacy and safety of stereotactic body radiation therapy (SBRT) in elderly patients with small hepatocellular carcinomas (HCC).

Methods

Eighty-three patients (89 lesions) with HCC who underwent SBRT between January 2012 and December 2018 were reviewed in this retrospective observational study. The key inclusion criteria were as follows: 1) age ≥75 years, 2) contraindications for hepatic resection or percutaneous ablative therapies, 3) no macroscopic vascular invasion, and 4) no extrahepatic metastasis.

Results

The patients were 75-90 years of age, and 49 (59.0%) of them were male. Most patients (94.0%) had an Eastern Cooperative Oncology Group performance status of 0 or 1. Seventy-four patients (89.2%) had Child-Pugh class

SUBMITTER: Jang JY 

PROVIDER: S-EPMC10035735 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature