Seasonal variation of diarrhoeal pathogens among Guinea-Bissauan children under five years of age.

ABSTRACT:

Background

Diarrhoea remains a major cause of childhood morbidity and mortality in low-income countries (LICs). The frequency of diarrhoeal episodes may vary by season, yet few prospective cohort studies have examined seasonal variation among various diarrhoeal pathogens using multiplex qPCR to analyse bacterial, viral and parasitic pathogens.

Methods

We combined our recent qPCR data of diarrhoeal pathogens (nine bacterial, five viral and four parasitic) among Guinea-Bissauan children under five years old with individual background data, dividing by season. The associations of season (dry winter and rainy summer) and the various pathogens were explored among infants (0-11 months) and young children (12-59 months) and those with and without diarrhoea.

Results

Many bact

SUBMITTER: Mero S 

PROVIDER: S-EPMC10035853 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature