Chlorhexidine bathing in a tertiary care neonatal intensive care unit: A pilot study.

ABSTRACT:

Background

Concerns regarding potential risk of dermal irritation have led to the exclusion of NICU patients from the recommendation regarding the use of 2% chlorhexidine gluconate (CHG) wash for daily skin cleansing to reduce bloodstream infections. Our aim was to assess the safety of 2% CHG bathing in NICU patients.

Methods

The regulator required a stepwise study enrollment to three successive groups: term infants, followed by near-term and pre-term infants. For comparison, we used a cohort of matched controls. A propensity score-adjusted regression model was used to compare the groups.

Intervention

Infants were bathed thrice-weekly with 2% CHG-impregnated washcloths. Participant's skin was examined daily.

Results

Over a total of 661 days of treatment: 384,12

SUBMITTER: Bar-Meir M 

PROVIDER: S-EPMC10035923 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature