An Evolving Understanding of the Basis and Management of Vascular Complications of COVID-19: Where Do We Go From Here?

ABSTRACT: The COVID-19 pandemic led to millions of deaths worldwide after its emergence in 2020. The SARS-CoV-2 virus primarily affects respiratory function, but immune dysregulation leading to systemic inflammation, endothelial dysfunction, and coagulopathy can predispose to systemic complications including hematologic and vascular complications. Treatment strategies for patients with COVID-19 have rapidly evolved and the effectiveness and safety of antithrombotic agents have been evaluated in multiple clinical trials. The findings have spurred interest in the prevention and treatment of the hematologic and vascular complications of non-COVID-19 respiratory infections. This review is focused on hematological and vascular complications of COVID-19, including their pathophysiology, clinical manifesta

SUBMITTER: Szekely Y 

PROVIDER: S-EPMC10036296 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature