The perspectives of UK personnel towards current killing practices for laboratory rodents.

ABSTRACT: Rodents are the predominant species used for scientific research and must be humanely killed upon completion of the work. In the UK this is regulated by Schedule 1 of the Animals Scientific Procedures Act 1986, which lists permitted methodologies considered capable of humane killing, including overdose of an anaesthetic, exposure to carbon dioxide (CO₂) gas, dislocation of the neck and concussion of the brain by striking the cranium. Although all are permitted, operator motivations behind method selection and individual operator preference remain unknown. The views of 219 laboratory animal personnel on institutional availability and use of Schedule 1 killing methods for laboratory rodents were obtained. Only 10% of participants reported that all four methods were available at th

SUBMITTER: Clarkson JM 

PROVIDER: S-EPMC10036518 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature