¹⁸F-FDG PET/CT radiomics signature and clinical parameters predict progression-free survival in breast cancer patients: A preliminary study.

ABSTRACT:

Introduction

This study aimed to investigate the feasibility of predicting progression-free survival (PFS) in breast cancer patients using pretreatment ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) radiomics signature and clinical parameters.

Methods

Breast cancer patients who underwent ¹⁸F-FDG PET/CT imaging before treatment from January 2012 to December 2020 were eligible for study inclusion. Eighty-seven patients were randomly divided into training (n = 61) and internal test sets (n = 26) and an additional 25 patients were used as the external validation set. Clinical parameters, including age, tumor size, molecular subtype, clinical TNM stage, and laboratory findings were collected. Radiomics features were extr

SUBMITTER: Xu X 

PROVIDER: S-EPMC10036789 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature