Current status and prospects of regenerative medicine for spinal cord injury using human induced pluripotent stem cells: a review.

ABSTRACT: Spinal cord injury (SCI) is damage to the spinal cord due to trauma or health conditions, resulting in lesions in the spinal cord. Currently, available treatment includes surgical intervention to decompress or stabilize a dislocated loose spine, steroid drugs to reduce inflammation, and subsequent rehabilitation. As there is a rising number of SCI globally, radical treatments to recover spinal cord functions have become highly anticipated. The development of new treatments is indeed progressing. Various therapeutic drug candidates are being developed in clinical trials, including neuroprotective/neurotrophic factors, antibodies for repulsive guidance molecules, and cell transplantation. Among them, with advances in stem cell biology, cell transplantation therapy is currently a promising th

SUBMITTER: Inoue M 

PROVIDER: S-EPMC10036917 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature