On the correction of respiratory motion-induced image reconstruction errors in positron-emission tomography-guided radiation therapy.

ABSTRACT:

Background and purpose

Free breathing (FB) positron emission tomography (PET) images are routinely used in radiotherapy for lung cancer patients. Respiration-induced artifacts in these images compromise treatment response assessment and obstruct clinical implementation of dose painting and PET-guided radiotherapy. The purpose of this study is to develop a blurry image decomposition (BID) method to correct motion-induced image-reconstruction errors in FB-PETs.

Materials and methods

Assuming a blurry PET is represented as an average of multi-phase PETs. A four-dimensional computed-tomography image is deformably registered from the end-inhalation (EI) phase to other phases. With the registration-derived deformation maps, PETs at other phases can be deformed from a PET at the EI

SUBMITTER: Zhong H 

PROVIDER: S-EPMC10036920 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature