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Trends of Cirrhosis-related Mortality in the USA during the COVID-19 Pandemic.


ABSTRACT: Immunocompromised status and interrupted routine care may render patients with cirrhosis vulnerable to the coronavirus disease 2019 (COVID-19) pandemic. A nationwide dataset that includes more than 99% of the decedents in the U.S. between April 2012 and September 2021 was used. Projected age-standardized mortality during the pandemic were estimated according to prepandemic mortality rates, stratified by season. Excess deaths were determined by estimating the difference between observed and projected mortality rates. A temporal trend analysis of observed mortality rates was also performed in 0.83 million decedents with cirrhosis between April 2012 and September 2021 was included. Following an increasing trend of cirrhosis-related mortality before the pandemic, with a semiannual percentage c

SUBMITTER: Yeo YH 

PROVIDER: S-EPMC10037514 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature