Therapeutic preference for Alzheimer's disease treatments: a discrete choice experiment with caregivers and neurologists.

ABSTRACT:

Background

Alzheimer's disease (AD) is a major global health crisis in need of more effective therapies. However, difficult choices to optimize value-based care will need to be made. While identifying preferred therapeutic attributes of new AD therapies is necessary, few studies have explored how preferences may vary between the stakeholders. In this study, the trade-offs among key attributes of amyloid plaque-lowering therapies for AD were assessed using a discrete choice experiment (DCE) and compared between caregivers and neurologists.

Methods

An initial pilot study was conducted to identify the potentially relevant features of a new therapy. The DCE evaluated seven drug attributes: clinical effects in terms of delay in AD progression over the standard of care (SOC), vari

SUBMITTER: Dranitsaris G 

PROVIDER: S-EPMC10037811 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature