Risk of ischemic and hemorrhagic stroke in relation to cold spells in four seasons.

ABSTRACT:

Background

Cold winter weather increases the risk of stroke, but the evidence is scarce on whether the risk increases during season-specific cold weather in the other seasons. The objective of our study was to test the hypothesis of an association between personal cold spells and different types of stroke in the season-specific context, and to formally assess effect modification by age and sex.

Methods

We conducted a case-crossover study of all 5396 confirmed 25-64 years old cases with stroke in the city of Kaunas, Lithuania, 2000-2015. We assigned to each case a one-week hazard period and 15 reference periods of the same calendar days of other study years. A personal cold day was defined for each case with a mean temperature below the fifth percentile of the frequency distr

SUBMITTER: Vaiciulis V 

PROVIDER: S-EPMC10037875 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature