A scoping review on two-stage randomized preference trial in the field of mental health and addiction.

ABSTRACT:

Background

Randomized Controlled Trial is the most rigorous study design to test the efficacy and effectiveness of an intervention. Patient preference may negatively affect patient performance and decrease the generalizability of a trial to clinical population. Patient preference trial have particular implications in the field of mental health and addiction since mental health interventions are generally complex, blinding of intervention is often difficult or impossible, patients may have strong preference, and outcome measures are often subjective patient self-report which may be greatly influenced if patient's preference did not match with the intervention received.

Methods

In this review, we have surveyed the application of two-stage randomized preference trial with focus

SUBMITTER: Chen S 

PROVIDER: S-EPMC10037890 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature