Modeling of a single bipolar electrode with tines for irreversible electroporation delivery.

ABSTRACT: Irreversible electroporation (IRE) is a non-thermal tumor ablation technology employed to treat solid tumors not amenable to resection or thermal ablation. The IRE systems currently in clinical use deliver electrical pulses via multiple monopolar electrodes. This approach can present significant technical challenges due to the requirement for accurate placement of multiple electrodes and maintenance of parallel electrode alignment during pulse delivery. In this study, we sought to evaluate a novel IRE electrode configuration consisting of a single bipolar electrode with deployable tines. Using commercial finite element software predicted ablation outcomes, thermal damage, ablation sphericity, and energy delivery were calculated for existing monopolar and bipolar electrodes, and bipolar ele

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC10037907 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature