<i>E. coli</i> Common pili promote the fitness and virulence of a hybrid aEPEC/ExPEC strain within diverse host environments.

ABSTRACT: Pathogenic subsets of Escherichia coli include diarrheagenic (DEC) strains that cause disease within the gut and extraintestinal pathogenic E. coli (ExPEC) strains that are linked with urinary tract infections, bacteremia, and other infections outside of intestinal tract. Among DEC strains is an emergent pathotype known as atypical enteropathogenic E. coli (aEPEC), which can cause severe diarrhea. Recent sequencing efforts revealed that some E. coli strains possess genetic features that are characteristic of both DEC and ExPEC isolates. BA1250 is a newly reclassified hybrid strain with characteristics of aEPEC and ExPEC. This strain was isolated from a child with diarrhea, but its genetic features indicate that it might have the capacity to cause disease at extr

SUBMITTER: Munhoz DD 

PROVIDER: S-EPMC10038029 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature