Factors correlated with pain after total knee arthroplasty: A systematic review and meta-analysis.

ABSTRACT:

Main objective

Systematically review and synthesize preoperative and intraoperative factors associated with pain after total knee arthroplasty (TKA) in patients with osteoarthritis.

Methods

Based on a peer-reviewed protocol, we searched Medline, Embase, CINAHL, Cochrane Library, and PEDro for prospective observational studies (January 2000 to February 2023) investigating factors associated with pain after TKA. The primary outcome was pain twelve months after TKA. Pain at three and six months were secondary outcomes. Multivariate random-effects meta-analyses were used to estimate mean correlation (95% CIs) between factors and pain. Sensitivity analysis was performed for each risk of bias domain and certainty of evidence was assessed.

Results

Of 13,640 studies, 29 repor

SUBMITTER: Olsen U 

PROVIDER: S-EPMC10038299 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature