Methods of arterial stiffness calculation and cardiovascular disease events: the multiethnic study of atherosclerosis.

ABSTRACT:

Background

A wide variety of different formulae have been used to calculate local arterial stiffness with little external validation in relationship to cardiovascular events. We compared the associations of several arterial stiffness calculations in a large, multiethnic cohort.

Methods

The multi-ethnic study of atherosclerosis (MESA) is a longitudinal study of 6814 adults without clinical cardiovascular disease (CVD) at enrollment. MESA participants with CVD surveillance through year 2018 and carotid ultrasound ( n  = 5873) or aorta MRI ( n  = 3175) at the baseline exam (2000-2002) were included. We analyzed 21 different calculations of local arterial stiffness. Cross-sectional and longitudinal statistical analyses were performed in addition to Cox hazard modeling for associ

SUBMITTER: Pewowaruk RJ 

PROVIDER: S-EPMC10038853 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature