Time to early resuscitative intervention association with mortality in trauma patients at risk for hemorrhage.

ABSTRACT:

Background

Hemorrhage is the leading cause of preventable death after injury. Others have shown that delays in massive transfusion cooler arrival increase mortality, while prehospital blood product resuscitation can reduce mortality. Our objective was to evaluate if time to resuscitation initiation impacts mortality.

Methods

We combined data from the Prehospital Air Medical Plasma (PAMPer) trial in which patients received prehospital plasma or standard care and the Study of Tranexamic Acid during Air and ground Medical Prehospital transport (STAAMP) trial in which patients received prehospital tranexamic acid or placebo. We evaluated the time to early resuscitative intervention (TERI) as time from emergency medical services arrival to packed red blood cells, plasma, or trane

SUBMITTER: Deeb AP 

PROVIDER: S-EPMC10038862 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature