Exploring the genetics of rhythmic perception and musical engagement in the Vanderbilt Online Musicality Study.

ABSTRACT: Uncovering the genetic underpinnings of musical ability and engagement is a foundational step for exploring their wide-ranging associations with cognition, health, and neurodevelopment. Prior studies have focused on using twin and family designs, demonstrating moderate heritability of musical phenotypes. The current study used genome-wide complex trait analysis and polygenic score (PGS) approaches utilizing genotype data to examine genetic influences on two musicality traits (rhythmic perception and music engagement) in N = 1792 unrelated adults in the Vanderbilt Online Musicality Study. Meta-analyzed heritability estimates (including a replication sample of Swedish individuals) were 31% for rhythmic perception and 12% for self-reported music engagement. A PGS derived from a recent study o

SUBMITTER: Gustavson DE 

PROVIDER: S-EPMC10038917 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature