The incidence of vertebral compression fractures and spinal instability in newly diagnosed multiple myeloma patients.

ABSTRACT:

Background

Multiple myeloma (MM) is a hematologic malignancy, characterized by clonal proliferation of plasma cells in the bone marrow. These plasma cell proliferations frequently result in scattered osteolytic bone lesions and extensive skeletal destruction. Myeloma bone lesions are frequently located in the spine, and are associated with debilitating bone pain and an increased rate of pathologic fractures and mortality. The aim of this study was to investigate the incidence of vertebral compression fractures (VCFs) and spinal instability in patients with MM.

Patients and methods

Newly diagnosed patients with MM with computed tomography (CT) scans of the spine within three months of diagnosis were identified through an electronic patient database. Clinical baseline data wer

SUBMITTER: Zijlstra H 

PROVIDER: S-EPMC10038922 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature