The spine and carina as a surrogate for target registration in cone-beam CT imaging verification in locally advanced lung cancer radiotherapy.

ABSTRACT:

Background

The aim of the study was to evaluate the accuracy of volumetric lung image guidance using the spine or carina as a surrogate to target for image registration, as the best approach is not established.

Patients and methods

Cone beam computed tomography images from the 1^st, 10^th, 15^th, and 20^th fraction in 40 lung cancer patients treated with radical radiotherapy were retrospectively registered to planning CT, using three approaches. The spine and carina alignment set-up deviations from a reference (tumour/lymph nodes) registration in the lateral (LAT), longitudinal (LONG) and vertical (VRT) directions were analysed and compared. Tumour location and nodal stage influence on registration accuracy were explored.

Results

SUBMITTER: But-Hadzic J 

PROVIDER: S-EPMC10039477 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature