Luteolin intake is negatively associated with all-cause and cardiac mortality among patients with type 2 diabetes mellitus.

ABSTRACT:

Background

Luteolin, a common flavonoid in our daily diet, has potent anti-diabetic effects. However, its prognostic impact on type 2 diabetes mellitus (T2DM) is still uncertain. This study aimed to clarify this association.

Methods

In this prospective cohort study, 2,461 patients with T2DM were included from the National Health and Nutrition Examination Survey. Dietary luteolin intake was estimated by the type and amount of food consumed in a 24-hour dietary recall. All-cause and cardiac mortality were ascertained by National Death Index Mortality data (as of December 31, 2019). The association of luteolin intake with mortality risk was estimated by Cox proportional hazards model.

Results

The median (interquartile range) luteolin intake was 0.355 (0.130, 0.835) mg/da

SUBMITTER: Zhang W 

PROVIDER: S-EPMC10039598 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature