Alcohol consumption and microvascular dysfunction: a J-shaped association: The Maastricht Study.

ABSTRACT:

Background

Microvascular dysfunction (MVD) is an important contributor to major clinical disease such as stroke, dementia, depression, retinopathy, and chronic kidney disease. Alcohol consumption may be a determinant of MVD.

Objective

Main objectives were (1) to study whether alcohol consumption was associated with MVD as assessed in the brain, retina, skin, kidney and in the blood; and (2) to investigate whether associations differed by history of cardiovascular disease or sex.

Design

We used cross-sectional data from The Maastricht Study (N = 3,120 participants, 50.9% men, mean age 60 years, and 27.5% with type 2 diabetes [the latter oversampled by design]). We used regression analyses to study the association between total alcohol (per unit and in the categories, i

SUBMITTER: van der Heide FCT 

PROVIDER: S-EPMC10039613 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature