Association between multidimensional prognostic index (MPI) and infections in a population of older people affected by COVID-19.

ABSTRACT:

Background

Only limited studies analyzed a possible relationship between frailty and infections. Our aim was to investigate the possible association between higher multidimensional prognostic index (MPI) values, a tool for evaluating multidimensional frailty, and the prevalence of infectious diseases, including antibiotics' cost and the prevalence of MDR (multidrug resistance) pathogens.

Methods

Older patients, affected by COVID-19, were enrolled in the hospital of Palermo over four months.

Results

112 participants (mean age 77.6, 55.4% males) were included. After adjusting for potential confounders, frailer participants had a higher odds of any positivity to pathogens (prevalence: 61.5%, odds ratio = 15.56, p < 0.0001) compared to a prevalence of 8.6% in more robust,

SUBMITTER: Ragusa FS 

PROVIDER: S-EPMC10039674 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature