Neostigmine for the treatment of acute pancreatitis: a protocol for a systematic review and meta-analysis.

ABSTRACT:

Introduction

Acute pancreatitis (AP) is a common disease with substantial mortality. Gut dysfunction may result in abdominal compartment syndrome (ACS) and delay enteral nutrition, worsening AP condition. Neostigmine is used as a prokinetic drug for the treatment of AP. But there are no recommendations from guidelines due to the lack of evidence. Therefore, we plan to conduct a systematic review and meta-analysis to explore the efficacy and safety of neostigmine for AP, aiming to provide current evidence for clinical practice.

Methods and analysis

We prepared this protocol following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols. We will search the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, China National Knowledge Infr

SUBMITTER: He K 

PROVIDER: S-EPMC10040008 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature