Ambient air pollutants in the first trimester of pregnancy and birth defects: an observational study.

ABSTRACT:

Objectives

As current studies on the relationships between air pollutants exposure during the first trimester and birth defects were not fully elucidated, this study aimed to assess the association between selected air pollutants and birth defects.

Design

An observational study.

Participants

We obtained 70 854 singletons with gestational age <20 weeks who were delivered at a large maternal and child healthcare centre in Wuhan, China.

Outcome measures

Birth defects data and daily average concentration of ambient particulate matter ≤10 µm diameter (PM₁₀), PM ≤2.5 µm diameter (PM_2.5), sulfur dioxide (SO₂) and nitrogen dioxide (NO₂) were obtained. Logistic regression analysis was applied to assess the association between

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC10040071 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature