Safety of COVID-19 vaccines during pregnancy: A systematic review and meta-analysis.

ABSTRACT:

Background

Assessment of COVID-19 vaccines safety during pregnancy is urgently needed.

Methods

We conducted a systematic review and meta-analysis to evaluate the safety of COVID-19 vaccines, including their components and technological platforms used in other vaccines during pregnancy and animal studies to complement direct evidence. We searched literature databases from its inception to September 2021 without language restriction, COVID-19 vaccine websites, and reference lists of other systematic reviews and the included studies. Pairs of reviewers independently selected, data extracted, and assessed the risk of bias of the studies. Discrepancies were resolved by consensus. (PROSPERO CRD42021234185).

Results

We retrieved 8,837 records from the literature search; 71 s

SUBMITTER: Ciapponi A 

PROVIDER: S-EPMC10040368 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature