Leiomyomata, neonatal anthropometry, and pregnancy outcomes in singleton pregnancies.

ABSTRACT:

Purpose

To investigate the relationship of fibroids in pregnancy, preterm birth, and neonatal anthropometry.

Methods

Pregnant women (n = 2578) in the National Institute of Child Health and Human Development Fetal Growth Studies-Singletons cohort had up to six ultrasounds across pregnancy. Sonographers recorded fibroid number and volume of the three largest fibroids. Trained personnel measured neonatal anthropometry. Linear and logistic regression compared neonatal anthropometry and pregnancy outcomes among pregnancies with versus without fibroids. Causal mediation analysis evaluated preterm birth as a mediator.

Results

Average birthweight did not differ by fibroid status. However, compared with pregnancies without fibroids, neonates from pregnancies with single fibroi

SUBMITTER: Mitro SD 

PROVIDER: S-EPMC10040437 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature