Characteristics of pediatric patients with multiple sclerosis and related disorders infected with SARS-CoV-2.

ABSTRACT:

Background

Pediatric patients with multiple sclerosis (POMS) and related disorders, clinically isolated syndrome (CIS), myelin oligodendrocyte glycoprotein antibody disorder (MOGAD), and neuromyelitis optica spectrum disorder (NMOSD), are commonly treated with immunosuppressants. Understanding the impact of SARS-CoV-2 infection in patients may inform treatment decisions.

Objective

Characterize SARS-CoV-2 infection prevalence and severity among a cohort of patients with POMS and related disorders, as well as the impact of disease-modifying therapies (DMTs).

Methods

POMS and related disorders patients enrolled in a large, prospective registry were screened for COVID-19 during standard-of-care neurology visits. If confirmed positive of having infection, further analysis

SUBMITTER: Schreiner T 

PROVIDER: S-EPMC10040482 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature