Artificial intelligence-based ⁶⁸Ga-DOTATOC PET denoising for optimizing ⁶⁸Ge/⁶⁸Ga generator use throughout its lifetime.

ABSTRACT:

Introduction

The yield per elution of a ⁶⁸Ge/⁶⁸Ga generator decreases during its lifespan. This affects the number of patients injected per elution or the injected dose per patient, thereby negatively affecting the cost of examinations and the quality of PET images due to increased image noise. We aimed to investigate whether AI-based PET denoising can offset this decrease in image quality parameters.

Methods

All patients addressed to our PET unit for a ⁶⁸Ga-DOTATOC PET/CT from April 2020 to February 2021 were enrolled. Forty-four patients underwent their PET scans according to Protocol_FixedDose (150 MBq) and 32 according to Protocol_WeightDose (1.5 MBq/kg). Protocol_WeightDose examinations were processed using the Subtle PET software (Proto

SUBMITTER: Quak E 

PROVIDER: S-EPMC10040856 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature