MRI-based measurement of in vivo disc mechanics in a young population due to flexion, extension, and diurnal loading.

ABSTRACT:

Background

Intervertebral disc degeneration is often implicated in low back pain; however, discs with structural degeneration often do not cause pain. It may be that disc mechanics can provide better diagnosis and identification of the pain source. In cadaveric testing, the degenerated disc has altered mechanics, but in vivo, disc mechanics remain unknown. To measure in vivo disc mechanics, noninvasive methods must be developed to apply and measure physiological deformations.

Aim

Thus, this study aimed to develop methods to measure disc mechanical function via noninvasive MRI during flexion and extension and after diurnal loading in a young population. This data will serve as baseline disc mechanics to later compare across ages and in patients.

Materials & methods

To

SUBMITTER: Meadows KD 

PROVIDER: S-EPMC10041375 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature