Blood Pressure and Later-Life Cognition in Hispanic and White Adults (BP-COG): A Pooled Cohort Analysis of ARIC, CARDIA, CHS, FOS, MESA, and NOMAS.

ABSTRACT:

Background

Ethnic differences in cognitive decline have been reported. Whether they can be explained by differences in systolic blood pressure (SBP) is uncertain.

Objective

Determine whether cumulative mean SBP levels explain differences in cognitive decline between Hispanic and White individuals.

Methods

Pooled cohort study of individual participant data from six cohorts (1971-2017). The present study reports results on SBP and cognition among Hispanic and White individuals. Outcomes were changes in global cognition (GC) (primary), executive function (EF) (secondary), and memory standardized as t-scores (mean [SD], 50 [10]); a 1-point difference represents a 0.1 SD difference in cognition. Median follow-up was 7.7 (Q1-Q3, 5.2-20.1) years.

Results

We included 2

SUBMITTER: Levine DA 

PROVIDER: S-EPMC10041434 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature