Development and validation of an intuitive biomechanics-based method for intraocular pressure measurement: a modal analysis approach.

ABSTRACT:

Background

Current intraocular pressure (IOP) measurements based on non-contact tonometry are derived from statistics-driven equations and lack biomechanical significance, which often leads to under-estimation in post-refractive surgery cornea. This study aims to introduce and validate modal analysis-derived intraocular pressure (mIOP) as a novel method generated through Legendre-based modal decomposition of the anterior corneal contour; it provides an accurate and intuitive IOP measurement from an energy-based perspective.

Methods

This retrospective study included 680 patients. Healthy participants were divided into reference (n = 385) and validation (n = 142) datasets, and the others underwent either femtosecond-assisted laser in situ keratomileusis (FS-LASIK, n = 58) or t

SUBMITTER: Hsu FL 

PROVIDER: S-EPMC10041475 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature