Resequencing of a Pekin duck breeding population provides insights into the genomic response to short-term artificial selection.

ABSTRACT:

Background

Short-term, intense artificial selection drives fast phenotypic changes in domestic animals and leaves imprints on their genomes. However, the genetic basis of this selection response is poorly understood. To better address this, we employed the Pekin duck Z2 pure line, in which the breast muscle weight was increased nearly 3-fold after 10 generations of breeding. We denovo assembled a high-quality reference genome of a female Pekin duck of this line (GCA_003850225.1) and identified 8.60 million genetic variants in 119 individuals among 10 generations of the breeding population.

Results

We identified 53 selected regions between the first and tenth generations, and 93.8% of the identified variations were enriched in regulatory and noncoding regions. Integrating the

SUBMITTER: Yu S 

PROVIDER: S-EPMC10041536 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature