Multi-organ impairment and long COVID: a 1-year prospective, longitudinal cohort study.

ABSTRACT:

Objectives

To determine the prevalence of organ impairment in long COVID patients at 6 and 12 months after initial symptoms and to explore links to clinical presentation.

Design

Prospective cohort study.

Participants

Individuals.

Methods

In individuals recovered from acute COVID-19, we assessed symptoms, health status, and multi-organ tissue characterisation and function.

Setting

Two non-acute healthcare settings (Oxford and London). Physiological and biochemical investigations were performed at baseline on all individuals, and those with organ impairment were reassessed.

Main outcome measures

Primary outcome was prevalence of single- and multi-organ impairment at 6 and 12 months post COVID-19.

Results

A total of 536 individuals (mean age 4

SUBMITTER: Dennis A 

PROVIDER: S-EPMC10041626 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature