Optical coherence tomography angiography measurements in multiple sclerosis: a systematic review and meta-analysis.

ABSTRACT:

Background and objectives

Recent literature on multiple sclerosis (MS) demonstrates the growing implementation of optical coherence tomography-angiography (OCT-A) to discover potential qualitative and quantitative changes in the retina and optic nerve. In this review, we analyze OCT-A studies in patients with MS and examine its utility as a surrogate or precursor to changes in central nervous system tissue.

Methods

PubMed and EMBASE were systematically searched to identify articles that applied OCT-A to evaluate the retinal microvasculature measurements in patients with MS. Quantitative data synthesis was performed on all measurements which were evaluated in at least two unique studies with the same OCT-A devices, software, and study population compared to controls. A fixed-

SUBMITTER: Mohammadi S 

PROVIDER: S-EPMC10041805 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature