Radiologic and histopathologic features of hydrogel sealant after lung resection in participants of a prospective randomized clinical trial.

ABSTRACT:

Purpose

To summarize imaging and histopathologic characteristics of hydrogel sealant (plug) in lung parenchyma and assess their correlation with time since deployment of sealant.

Materials and methods

Among a total of 208 participants randomized to the hydrogel sealant arm of a lung biopsy prospective randomized clinical trial, 51 underwent resection of the biopsied lesion. In 34 participants sealant material was present on histopathologic sections (n = 22), or they had cross-sectional imaging of chest between biopsy and resection (n = 23) or they had both imaging and histopathology (n = 11). Histopathologic and imaging findings were described. The association of these findings with time since sealant deployment was evaluated using the Wilcoxon rank sum test.

Results

SUBMITTER: Moussa AM 

PROVIDER: S-EPMC10041988 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature