WHO cardiovascular disease risk prediction model performance in 10 regions, China.

ABSTRACT:

Objective

To validate the World Health Organization (WHO) non-laboratory-based cardiovascular disease risk prediction model in regions of China.

Methods

We performed an external validation of the WHO model for East Asia using the data set of China Kadoorie Biobank, an ongoing cohort study with 512 725 participants recruited from 10 regions of China from 2004-2008. We also recalculated the recalibration parameters for the WHO model in each region and evaluated the predictive performance of the model before and after recalibration. We assessed discrimination performance by Harrell's C index.

Findings

We included 412 225 participants aged 40-79 years. During a median follow-up of 11 years, 58 035 and 41 262 incident cardiovascular disease cases were recorded in women and

SUBMITTER: Yang S 

PROVIDER: S-EPMC10042093 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature