Association between COVID-19 and Male Fertility: Systematic Review and Meta-Analysis of Observational Studies.

ABSTRACT:

Purpose

Whether COVID-19 reduces male fertility remains requires further investigation. This meta-analysis and systematic review evaluated the impact of COVID-19 on male fertility.

Materials and methods

The literature in PubMed, Embase, MEDLINE, Web of Science, and Cochrane Library up to January 01, 2022 was systematically searched, and a meta-analysis was conducted to investigate the effect of COVID-19 on male fertility. Totally 17 studies with a total of 1,627 patients and 1,535 control subjects were included in our meta-analysis.

Results

Regarding sperm quality, COVID-19 decreased the total sperm count (p=0.012), sperm concentration (p=0.001), total motility (p=0.001), progressive sperm motility (p=0.048), and viability (p=0.031). Subgroup analyses showed that diff

SUBMITTER: Wang S 

PROVIDER: S-EPMC10042646 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature