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Is There a Relevant Clinical Impact in Differentiating Idiopathic versus Unexplained Male Infertility?


ABSTRACT:

Purpose

Overall, male factor infertility (MFI) accounts for up to 50% of etiologies of couple's infertility, with almost 30% of MFI cases being idiopathic in nature. Idiopathic MFI does not support a tailored treatment work-up in clinical practice. To investigate rates of and characteristics of men presenting for idiopathic versus unexplained primary infertility as compared with same-ethnicity, age-comparable fertile men.

Materials and methods

Demographic, clinical and laboratory data from 3,098 primary infertile men consecutively evaluated were analyzed and compared with those of 103 fertile controls. Idiopathic male infertility (IMI) was defined for abnormality at semen analysis with no previous history of diseases affecting fertility and normal findings on physical

SUBMITTER: Corsini C 

PROVIDER: S-EPMC10042653 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature