Understanding Treatment Decisions in Neuromyelitis Optica Spectrum Disorder: A Global Clinical Record Review with Patient Interviews.

ABSTRACT:

Introduction

We sought insights into neuromyelitis optica spectrum disorder (NMOSD) treatment practices worldwide.

Methods

Neurologists from the USA, Germany, Italy, Brazil, South Korea, and China completed an online survey, contributing clinical records for aquaporin-4 (AQP4) immunoglobulin G (IgG)-seropositive adults with NMOSD, which included patient demographics, diagnosis, maintenance treatment history, relapse occurrence, and severity. Interviewed patients receiving NMOSD maintenance therapy provided information about their diagnosis, treatment, perceptions about relapse severity or disease stability, and treatment switches.

Results

A total of 389 neurologists submitted clinical records for 1185 patients with AQP4-IgG-seropositive NMOSD; 33 patients with NMOSD w

SUBMITTER: Min JH 

PROVIDER: S-EPMC10043119 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature