Timing of Allergenic Food Introduction and Risk of Immunoglobulin E-Mediated Food Allergy: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Earlier egg and peanut introduction probably reduces risk of egg and peanut allergy, respectively, but it is uncertain whether food allergy as a whole can be prevented using earlier allergenic food introduction.

Objective

To investigate associations between timing of allergenic food introduction to the infant diet and risk of food allergy.

Data sources

In this systematic review and meta-analysis, Medline, Embase, and CENTRAL databases were searched for articles from database inception to December 29, 2022. Search terms included infant, randomized controlled trial, and terms for common allergenic foods and allergic outcomes.

Study selection

Randomized clinical trials evaluating age at allergenic food introduction (milk, egg, fish, shellfish, tree nuts

SUBMITTER: Scarpone R 

PROVIDER: S-EPMC10043805 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature