Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors.

ABSTRACT:

Importance

Epilepsy has been associated with cognitive impairment and potentially dementia in older individuals. However, the extent to which epilepsy may increase dementia risk, how this compares with other neurological conditions, and how modifiable cardiovascular risk factors may affect this risk remain unclear.

Objective

To compare the differential risks of subsequent dementia for focal epilepsy compared with stroke and migraine as well as healthy controls, stratified by cardiovascular risk.

Design, setting, and participants

This cross-sectional study is based on data from the UK Biobank, a population-based cohort of more than 500 000 participants aged 38 to 72 years who underwent physiological measurements and cognitive testing and provided biological samples at

SUBMITTER: Tai XY 

PROVIDER: S-EPMC10043806 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature