In Vivo Effect of a Nisin-Biogel on the Antimicrobial and Virulence Signatures of Canine Oral Enterococci.

ABSTRACT: Periodontal disease is a relevant oral disease in dogs and nisin-biogel has been previously proposed to be used in its control. Enterococci, as inhabitants of the oral cavity with a high genetic versatility, are a reliable bacterial model for antimicrobial studies. Our goal was to evaluate the in vivo influence of the long-term dental application of the nisin-biogel on the virulence and antimicrobial signatures of canine oral enterococci. Twenty dogs were randomly allocated to one of two groups (treatment group-TG with nisin-biogel dental application, or control group-CG without treatment) and submitted to dental plaque sampling at day 0 and after 90 days (T90). Samples were processed for Enterococcus spp. isolation, quantification, identification, molecular typing and

SUBMITTER: Cunha E 

PROVIDER: S-EPMC10044209 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature