Low-Level Tetracycline Resistance Gene tet(O)_3 in Campylobacter jejuni.

ABSTRACT: Campylobacter (C.) spp. are the most important foodborne, bacterial, and zoonotic pathogens worldwide. Resistance monitoring of foodborne bacterial pathogens is an important tool to control antimicrobial resistance as a part of the "One Health" approach. The detection and functionality of new resistance genes are of paramount importance in applying more effective screening methods based on whole genome sequencing (WGS). Most tetracycline-resistant C. spp. isolates harbor tet(O), a gene that encodes a ribosomal protection protein. Here we describe tet(O)_3, which has been identified in two food isolates of C. jejuni and is very similar to the tet(O) gene in Streptococcus pneumoniae, having a truncated promoter sequence. This gene confe

SUBMITTER: Pacifico C 

PROVIDER: S-EPMC10044288 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature