Maternal family history of urolithiasis is associated with earlier age of onset of stone disease.

ABSTRACT:

Purpose

To evaluate the impact of detailed family history on the severity of disease and age of onset in patients with urolithiasis.

Methods

Prospectively collected data from a single institution between October 2015 and December 2020 were analyzed. Our primary endpoint was the number of patients experiencing at least one recurrent stone during the follow-up period.

Results

Of 1566 patients analyzed, 603 (39%) reported at least one family member with a history of stones. The percentage of patients experiencing at least one recurrent stone event was higher in patients with a family history of stones (38%) compared to those without a family history of stones (28%) over a median follow-up period of 8 months (p = 0.001). On multivariate analysis, the presence of any famil

SUBMITTER: Unno R 

PROVIDER: S-EPMC10044450 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature