Selective Enzymatic Esterification of Lignin-Derived Phenolics for the Synthesis of Lipophilic Antioxidants.

ABSTRACT: Lignin is an abundant and renewable source of phenolic compounds that can be used as natural antioxidants to substitute synthetic, petroleum-based alternatives. The development of lignin depolymerization techniques has improved the accessibility of low-molecular-weight phenolic fractions with enhanced antioxidant activity compared to native lignin. The selective esterification of the aliphatic OH groups in these compounds is necessary in order to increase their compatibility with hydrophobic product matrixes, while preserving their antioxidant capacity. In the present work, lipase was chosen as a selective catalyst for the esterification of the monolignol dihydroconiferyl alcohol (DCA), in order to target the esterification of aliphatic OHs without modifying the aromatic groups. The reacti

SUBMITTER: Martinez-Garcia M 

PROVIDER: S-EPMC10045519 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature