Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA.

ABSTRACT: We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tickborne viruses to enhance encephalitis diagnosis and management.

SUBMITTER: Farrington M 

PROVIDER: S-EPMC10045675 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature