From In Silico to a Cellular Model: Molecular Docking Approach to Evaluate Antioxidant Bioactive Peptides.

ABSTRACT: The increasing need to counteract the redox imbalance in chronic diseases leads to focusing research on compounds with antioxidant activity. Among natural molecules with health-promoting effects on many body functions, bioactive peptides are gaining interest. They are protein fragments of 2-20 amino acids that can be released by various mechanisms, such as gastrointestinal digestion, food processing and microbial fermentation. Recent studies report the effects of bioactive peptides in the cellular environment, and there is evidence that these compounds can exert their action by modulating specific pathways. This review focuses on the newest approaches to the structure-function correlation of the antioxidant bioactive peptides, considering their molecular mechanism, by evaluating the activa

SUBMITTER: Tonolo F 

PROVIDER: S-EPMC10045749 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature