Protection from Omicron Infection in Residents of Nursing and Retirement Homes in Ontario, Canada.

ABSTRACT:

Objectives

To identify factors that contribute to protection from infection with the Omicron variant of SARS-CoV-2 in older adults in nursing and retirement homes.

Design

Longitudinal cohort study with retrospective analysis of infection risk.

Setting and participants

997 residents of nursing and retirement homes from Ontario, Canada, in the COVID in LTC study.

Methods

Residents with 3 messenger RNA (mRNA) dose vaccinations were included in the study. SARS-CoV-2 infection was determined by positive nasopharyngeal polymerase chain reaction test and/or circulating antinucleocapsid IgG antibodies. Cumulative probability of Omicron infection after recent COVID-19 was assessed by log-rank test of Kaplan-Meier curves. Cox regression was used to assess risk of Omicron

SUBMITTER: Breznik JA 

PROVIDER: S-EPMC10046272 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature