Programming DNA Reaction Networks Using Allosteric DNA Hairpins.

ABSTRACT: The construction of DNA reaction networks with complex functions using various methods has been an important research topic in recent years. Whether the DNA reaction network can perform complex tasks and be recycled directly affects the performance of the reaction network. Therefore, it is very important to design and implement a DNA reaction network capable of multiple tasks and reversible regulation. In this paper, the hairpin allosteric method was used to complete the assembly task of different functional nucleic acids. In addition, information conversion of the network was realized. In this network, multiple hairpins were assembled into nucleic acid structures with different functions to achieve different output information through the cyclic use of trigger strands. A method of single-

SUBMITTER: Qin R 

PROVIDER: S-EPMC10046357 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature